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Synergy Between Phorbol Esters and Retinoic Acid in Inducing Protein Kinase C Activation

✍ Scribed by H. Bouzinbasegard; X.T. Fan; M. Perderiset; M. Castagna

Book ID
115575459
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
408 KB
Volume
204
Category
Article
ISSN
0006-291X

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## Abstract Treatment with 300 nM phorbol 12‐myristate 13‐acetate (PMA) transforms polygonal‐shaped cultured astrocytes into process‐bearing cells and produces a shift in protein kinase C (PK‐C) from the cytosol to the membrane. Exposure to PMA also produces increases in the phosphorylation of seve