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Synergistic potentiation of polyphosphoinositide breakdown by adenylate cyclase coupled receptors in human endothelial cells

✍ Scribed by T.A. Voino-Yasenetskaya; G.Y. Grigorian; S.M. Danilov; T.J. Resink; V.A. Tkachuk; V.S. Repin

Book ID
115980608
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
392 KB
Volume
21
Category
Article
ISSN
0022-2828

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## Abstract The level of adhesion molecules expressed at the endothelial cell surface is critical in the control of inflammation. Adenylate cyclase (AC) activity allowing cyclic adenosine monophosphate (cAMP) production can modulate the inflammatory process. We investigated the AC‐dependent modulat