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Synergistic modulation of ectoCa2+-ATPase activity of hepatoma (Li-7A) cells by epidermal growth factor and cyclic AMP

โœ Scribed by Aileen F. Knowles

Book ID
115708602
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
751 KB
Volume
283
Category
Article
ISSN
0003-9861

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Inhibition of growth and induction of en
Inhibition of growth and induction of enzyme activities in a clonal human hepatoma cell line (Li-7A): Comparison of the effects of epidermal growth factor and an anti-epidermal growth factor receptor antibody
โœ Aileen F. Knowles ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 780 KB

A cloned human hepatoma cell line (Li-7A), possessing epidermal growth factor (EGF) receptors numbering in the range of 10-20 pmol/106 cells, was inhibited in its growth by EGF as well as an antagonist monoclonal antibody (MoAb) to the EGF receptor. The mode of action of the two ligands of EGF recep