𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synergistic induction of nitric oxide synthase type II: In vitro effect of leptin and interferon-γ in human chondrocytes and ATDC5 chondrogenic cells

✍ Scribed by Miguel Otero; Juan Jesús Gomez Reino; Oreste Gualillo


Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
133 KB
Volume
48
Category
Article
ISSN
0004-3591

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Synergistic activation of NF-κb and indu
✍ Nobuo Sekine; Toshio Ishikawa; Tomoki Okazaki; Michio Hayashi; Claes B. Wollheim 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 332 KB 👁 1 views

Interferon-gamma (IFN-gamma) is known to exert deleterious effects on pancreatic beta-cells and is implicated in the development of type 1 (autoimmune) diabetes mellitus. In this study, we investigated signaling mechanisms mediating the effects of IFN-gamma in pancreatic beta-cells using a different

Synergistic expression of inducible nitr
✍ Inn-Oc Han; Hee-Sun Kim; Hyoung-Chun Kim; Eun-Hye Joe; Won-Ki Kim 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 271 KB

## Abstract A proinflammatory cytokine IFN‐γ stimulates microglia in the injured brain; however, signaling pathways for IFN‐γ‐mediated microglia activation are not well characterized. In the present study, a protein kinase C (PKC) activator phorbol 12‐myristate 13‐acetate (PMA) acts in concert with

Involvement of protein kinase Cζ in inte
✍ Priya S. Chockalingam; Usha Varadarajan; Richard Sheldon; Eric Fortier; Edward R 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 334 KB 👁 1 views

## Abstract ## Objective Protein kinase Cζ (PKCζ), an atypical PKC, has been found to be transcriptionally up‐regulated in human osteoarthritic (OA) articular cartilage. This study was undertaken to examine the role of PKCζ in interleukin‐1β (IL‐1β)–induced NF‐κB signaling in human OA chondrocytes