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Synergistic heterozygosity in mice with inherited enzyme deficiencies of mitochondrial fatty acid β-oxidation

✍ Scribed by A. Michele Schuler; Barbara A. Gower; Dietrich Matern; Piero Rinaldo; Jerry Vockley; Philip A. Wood


Book ID
116987569
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
369 KB
Volume
85
Category
Article
ISSN
1096-7192

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Regulation of mitochondrial fatty acid β
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The mitochondrial fatty acid β-oxidation (FAO) pathway plays a crucial role in ATP production in many tissues with high-energy demand. This is highlighted by the diverse and possibly severe clinical manifestations of inborn fatty acid β-oxidation deficiencies. More than fifteen genetic FAO enzyme de