Synergistic Effects on Enantioselectivity of Zwitterionic Chiral Stationary Phases for Separations of Chiral Acids, Bases, and Amino Acids by HPLC
✍ Scribed by Hoffmann, Christian V.; Pell, Reinhard; Lämmerhofer, Michael; Lindner, Wolfgang
- Book ID
- 125834615
- Publisher
- American Chemical Society
- Year
- 2008
- Tongue
- English
- Weight
- 478 KB
- Volume
- 80
- Category
- Article
- ISSN
- 0003-2700
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📜 SIMILAR VOLUMES
An extensive series of free amino acids and analogs were directly resolved into enantiomers (and stereoisomers where appropriate) by HPLC on zwitterionic chiral stationary phases (Chiralpak ZWIX(+) and Chiralpak ZWIX(−)). The interaction and chiral recognition mechanisms were based on the synergisti
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## Abstract A __tert__‐butylcarbamoylquinine‐based chiral stationary phase (Chiralpak QN‐AX) has been employed for the enantiomer separation of underivatized chiral acidic amino acids, viz. 4‐carboxyphenylalanine (4‐CPHE), 1‐aminoindan‐1,5‐dicarboxylic acid (AIDA), 2‐(5‐carboxy‐3‐methyl‐2‐thienyl)g