Synergistic effect of two oxidative stress-related genes (heme oxygenase-1 and GSK3β) on the risk of Parkinson’s disease

Study on the ability of 1,2,3,4-tetrahyd

Study on the ability of 1,2,3,4-tetrahydropapaveroline to cause oxidative stress: Mechanisms and potential implications in relation to parkinson's disease

✍ Ramón Soto-Otero; Carolina Sanmartín-Suárez; Sofía Sánchez-Iglesias; Álvaro Herm 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 341 KB

## Abstract Tetrahydropapaveroline (THP) is a compound derived from dopamine monoamine oxidase–mediated metabolism, particularly present in the brain of parkinsonian patients receiving L‐dopa therapy, and is capable of causing dopaminergic neurodegeneration. The aim of this work was to evaluate the