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Synergistic effect of interleukin (IL)-1α and ceramide analogue on the production of IL-6, IL-8, and macrophage colony-stimulating factor by endometrial stromal cells

✍ Scribed by Yasushi Kawano; Junichiro Fukuda; Kaei Nasu; Harunobu Matsumoto; Hisashi Narahara; Isao Miyakawa


Book ID
118443897
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
208 KB
Volume
82
Category
Article
ISSN
1556-5653

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Human bone marrow stromal cells repond to stimulation by the monokines IL-1 and TNF by producing colony-stimulating factors such as GM-CSF and G-CSF. In this study we show that I L -l a and TNFa act synergistically to stimulate GM-CSF and G-CSF production by cultured marrow stromal cells. We further