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Synergistic effect of IL-12 and IL-18 in driving intestinal Th1-mediated inflammation in Crohn's disease

✍ Scribed by Akira Okazawa; Takanori Kanai; Mamoru Watanabe; Toshiro Sate; Nagamu Inoue; Hiromasa Ishii; Masao Ikeda; Masashi Kurimoto; Toshifumi Hibi

Book ID
119425649
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
179 KB
Volume
118
Category
Article
ISSN
0016-5085

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✍ Anje A. te Velde; Yvette van Kooyk; Henri Braat; Daan W. Hommes; Trees A. M. Del πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 458 KB

Dentritic cells (DC) as antigen-presenting cells are most likely responsible for regulation of abnormal T cell activation in Crohn's disease (CD), a chronic inflammatory bowel disease. We have analyzed the expression of activation and maturation markers on DC in the colon mucosa from patients with C