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Synergistic effect of 5-fluorouracil and the flavanoid oroxylin A on HepG2 human hepatocellular carcinoma and on H22transplanted mice

โœ Scribed by Li Zhao; Zhen Chen; Jun Wang; Li Yang; Qing Zhao; Jia Wang; Qi Qi; Rong Mu; Qi-Dong You; Qing-Long Guo


Publisher
Springer
Year
2009
Tongue
English
Weight
403 KB
Volume
65
Category
Article
ISSN
0344-5704

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Effect of a xanthine analog on human hep
โœ L Marucci; L Varticovski; I M Arias ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 671 KB

Hepatocellular carcinoma (HCC) frequently overexpresses the MDR1 gene and is resistant to drugs transported by the multidrug-resistance efflux pump. A xanthine analog, 1-(11-dodecylamino-10-hydroxyundecyl)-3,7-dimethylxanthine (CT-2584,CTI), is cytotoxic to many tumors in culture and was four times