## Background: Bioincompatible glucose degradation products (gdps) in fluids for peritoneal dialysis (pd) develop during sterilization and storage. their biological activity has successfully been monitored through the use of various in vitro methods but their molecular and chemical nature is less w
Synergistic cytotoxicity of acidity and glucose degradation products in peritoneal dialysis fluid
β Scribed by Eiji Okabe; Tadashi Tomo; Kazuhito Tezono; Hiroshi Kikuchi; Jyun-ichi Kadota; Masaru Nasu
- Book ID
- 106256665
- Publisher
- Springer
- Year
- 2004
- Tongue
- English
- Weight
- 443 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1434-7229
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π SIMILAR VOLUMES
Conventional fluids for peritoneal dialysis (PD) contain reactive glucose degradation products (GDPs) as a result of glucose breakdown during heat-sterilization. GDPs in PD fluids (PDFs) have been associated with the progressive alteration of the peritoneal membrane during long-term PD by cytotoxic
## Abstract Peritoneal dialysis (PD) is commonly performed by using preprepared dialysis solutions containing glucose, which are thermally treated to achieve commercial sterilization. A series of glucose degradation products (GDPs) are being formed, which react with the tissue during the dialysis p