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Synergistic activity of letrozole and sorafenib on breast cancer cells

โœ Scribed by Mara A. Bonelli; Claudia Fumarola; Roberta R. Alfieri; Silvia La Monica; Andrea Cavazzoni; Maricla Galetti; Rita Gatti; Silvana Belletti; Adrian L. Harris; Stephen B. Fox; Dean B. Evans; Mitch Dowsett; Lesley-Ann Martin; Alberto Bottini; Daniele Generali; Pier Giorgio Petronini


Book ID
106378565
Publisher
Springer US
Year
2010
Tongue
English
Weight
551 KB
Volume
124
Category
Article
ISSN
0167-6806

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## Abstract Four and a half LIM domain protein 2 (FHL2) has been implicated in development and progression of various types of cancers. However, little is known about the biological function of FHL2 in breast cancer. Here, we report that FHL2 physically and functionally interacts with estrogen rece