## Abstract We have attempted to determine what host mechanisms are responsible for inducing a rapid decrease in the number of Friend leukemia cells (FLC) in the peritoneal cavity of interferon‐treated mice. By injecting radiolabelled FLC, we showed that there was a greater loss of radioactivity fr
Synergism in the antitumor effects of type 1 and type II interferon in mice inoculated with leukemia L1210 cells
✍ Scribed by De Clercq, Erik; Zhang, Zhen-Xi; Huygen, Kris
- Book ID
- 122907954
- Publisher
- Elsevier Science
- Year
- 1982
- Tongue
- English
- Weight
- 392 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0304-3835
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## Abstract Interferon‐sensitive (745) and interferon‐resistant (3Cl‐8) Friend leukemia cells (FLC) are highly tumorigenic for DBA/2 mice. The phenotype of interferon sensitivity or resistance does not change with __in vivo__ passage. Daily administration of mouse interferon markedly enhanced the s
## Abstract Administration of highly purified interferon to DA/2 mice inhibited the growth of interferon‐sensitive or interferon‐resistant Friend erythroleukemia cells implanted subcutaneously. Injection of interferon at the site of tumor inoculation was more effective than injection of interferon