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Synergism between the responses to LPS and to allergen of the murine airways: role and limitations of TNFα

✍ Scribed by M.D. Possebon da Silva; J. Lefort; M. Nahori; C. Dumarey; C. Ruffié; C. Naspitz; B.B. Vargaftig


Book ID
117614945
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
77 KB
Volume
149
Category
Article
ISSN
0923-2494

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## Abstract **BACKGROUND:** We observed previously that tumor necrosis factor α (TNFα)–knockout embryos are more sensitive to a cyclophosphamide (CP)–induced teratogenic insult than their TNFα‐positive counterparts, implicating molecules acting in TNFα‐activated antiapoptotic pathways in the mechan