## Abstract The activation of microglia and astrocytes in the spinal cord is involved in the progress of cancer pain. Propentofylline (PPF), a glial modulating agent, alleviates pain hypersensitivity in neuropathic pain models. The present study investigated the potential roles of PPF in a preclini
✦ LIBER ✦
Synergetic Analgesia of Propentofylline and Electroacupuncture by Interrupting Spinal Glial Function in Rats
✍ Scribed by Ling-Li Liang; Jia-Le Yang; Ning Lü; Xi-Yao Gu; Yu-Qiu Zhang; Zhi-Qi Zhao
- Publisher
- Springer
- Year
- 2010
- Tongue
- English
- Weight
- 378 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0364-3190
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## Abstract It is well established that axons of the adult mammalian CNS are capable of regrowing only a limited amount after injury. Astrocytes are believed to play a crucial role in the failure to regenerate, producing multiple inhibitory proteoglycans, such as chondroitin sulphate proteoglycans