In murine myocarditis, it has been shown that natural killer cells first infiltrate the heart, followed by activated T-cells, which play an important role in the pathogenesis of the myocardial damage. In the same model of acute myocarditis, the repertoire of T-cell receptor (TCR) V p genes in infilt
โฆ LIBER โฆ
Syndrome of opsoclonus-myoclons caused by coxsackie B3 infection
โ Scribed by Karl C. Kuban; Moshe A. Ephros; Roy L. Freeman; Lori Burtz Laffell; Michael J. Bresnan
- Publisher
- John Wiley and Sons
- Year
- 1983
- Tongue
- English
- Weight
- 322 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0364-5134
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T-cell-mediated myocardial damage has been shown to be involved in acute myocarditis and dilated cardiomyopathy. It is necessary for T-cells to receive a co-stimulatory signal as well as the main signal through the T-cell receptor for antigen-specific T-cell activation to occur. To investigate the r