Syndecan-4-mediated signalling
β Scribed by Michael Simons; Arie Horowitz
- Book ID
- 114283593
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 179 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0898-6568
No coin nor oath required. For personal study only.
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Syndecans are transmembrane proteoglycans which can participate in diverse cell surface interactions, involving extracellular matrix macromolecules, growth factors, protease inhibitors, and even viral entry. Currently, all extracellular interactions are believed to be mediated by distinct structures
## Abstract Protease nexinβ1 (PNβ1), an inhibitor of serine proteases, contributes to tissue homeostasis and influences the behavior of some tumor cells. The internalization of PNβ1 protease complexes is considered to be mediated by the lowβdensity lipoprotein receptor related protein 1 (LRP1). In