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Syndecan-1 (CD138) expression in human breast carcinoma is associated with an aggressive phenotype and appears related to a poor prognosis and low response to adjuvant chemotherapy

✍ Scribed by E. Galligioni; M. Barbareschi; D. Aldovini; P. Maisonneuuve; M.G. Cangi; L. Pecciarini; O. Caffo; C. Arcuri; P. Dalla Palma; C. Doglioni

Book ID: 117658518
Publisher: Elsevier Science
Year: 2001
Tongue: English
Weight: 175 KB
Volume: 37
Category: Article
ISSN: 0959-8049
DOI: 10.1016/s0959-8049(01)81155-2

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High syndecan-1 expression in breast car

High syndecan-1 expression in breast carcinoma is related to an aggressive phenotype and to poorer prognosis

✍ Mattia Barbareschi; Patrick Maisonneuve; Daniela Aldovini; Maria Giulia Cangi; L 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 394 KB

## Abstract ## BACKGROUND Syndecan‐1 is a transmembrane heparan sulphate proteoglycan that is involved in cell–cell adhesion, organization of cell–matrix adhesion, and regulation of growth factor signaling. ## METHODS Specimens from 254 consecutive breast carcinoma (BC) cases (110 N0, 144 N1/2)