Synaptonemal complex analysis in a human male carrier of a 4;6 translocation: heterosynapsis without previous homosynapsis

✍ Scribed by A. Perdigo; O. Gabriel-Robez; C. Ratoinponirina; Y. Rumpler

• Publisher: Springer
• Year: 1991
• Tongue: English
• Weight: 691 KB
• Volume: 86
• Category: Article
• ISSN: 0340-6717
• DOI: 10.1007/bf00202409

✦ Synopsis

Silver-stained synaptonemal complexes in surface-spread pachytene nuclei from a man, heterozygous for a reciprocal translocation, were analysed by electron microscopy. Contrary to the classically expected cross-shaped configuration, extensive non-homologous pairings were observed with asymetrical association in the lateral elements of the non-homologous arms of the quadrivalents. A possible role of the heterosynapsis in reproductive failure is discussed.