The importance of glial cells in controlling the neuronal microenvironment has been increasingly recognized. We now demonstrate that glial cells play an integral role in hippocampal synaptic transmission by using the glial-specific metabolic blocker fluoroacetate (FAC) to selectively inhibit glial c
✦ LIBER ✦
Synaptic processes—The role of glial cells
✍ Scribed by Joachim W. Deitmer; Christian Steinhäuser
- Book ID
- 113506434
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 93 KB
- Volume
- 63
- Category
- Article
- ISSN
- 0165-0173
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Metabolic integrity of glial cells in field CA1 of the guinea pig hippocampus is critical to maintenance of synaptic transmission (Keyser and Pellmar [1994] Glia 10:237-243). To determine if this tight glial-neuronal coupling is equally important in other brain regions, we compared the effect of flu