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Synaptic Accumulation of PSD-95 and Synaptic Function Regulated by Phosphorylation of Serine-295 of PSD-95

✍ Scribed by Myung Jong Kim; Kensuke Futai; Jihoon Jo; Yasunori Hayashi; Kwangwook Cho; Morgan Sheng


Book ID
116783092
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
172 KB
Volume
57
Category
Article
ISSN
0896-6273

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## Abstract The persistent activity of protein kinase Mzeta (PKMΞΆ), a brain‐specific, constitutively active protein kinase C isoform, maintains synaptic long‐term potentiation (LTP). Structural remodeling of the postsynaptic density is believed to contribute to the expression of LTP. We therefore e