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Syn -Selective Michael Addition of Amines to Bis-Enones: Synthesis of 1,3,4,7-Tetrasubstituted (4 R ,5 S ,6 S ,7 R )-Hexahydro-5,6-dihydroxy-2 H -1,3-diazepin-2-ones †

✍ Scribed by Schreiner, Erwin P.; Pruckner, Arno


Book ID
120788543
Publisher
American Chemical Society
Year
1997
Tongue
English
Weight
157 KB
Volume
62
Category
Article
ISSN
0022-3263

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ChemInform Abstract: Syn-Selective Micha
✍ E. P. SCHREINER; A. PRUCKNER 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 37 KB 👁 1 views

Syn-Selective Michael Addition of Amines to Bis-enones: Synthesis of 1, 3,4,7-Tetrasubstituted (4R,5S,6S,7R)-Hexahydro-5,6-dihydroxy-2H-1,3-diazepin-2-ones. -The O-protected title compounds (IX), seven-membered cyclic ureas, are useful as intermediates in the synthesis of HIV-proteinase inhibitors.