ChemInform Abstract: Syn-Selective Micha
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E. P. SCHREINER; A. PRUCKNER
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Article
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2010
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John Wiley and Sons
⚖ 37 KB
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Syn-Selective Michael Addition of Amines to Bis-enones: Synthesis of 1, 3,4,7-Tetrasubstituted (4R,5S,6S,7R)-Hexahydro-5,6-dihydroxy-2H-1,3-diazepin-2-ones. -The O-protected title compounds (IX), seven-membered cyclic ureas, are useful as intermediates in the synthesis of HIV-proteinase inhibitors.