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Symptoms as predictors of response to amitriptyline and nortriptyline: The plasma level variable

✍ Scribed by William Coryell; Vincent E. Ziegler; John T. Biggs


Book ID
118388152
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
673 KB
Volume
2
Category
Article
ISSN
0165-0327

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The demethylation of amitriptyline: A cr
✍ J. E. Burch πŸ“‚ Article πŸ“… 1983 πŸ› Springer 🌐 English βš– 506 KB

Five elderly depressed patients were treated with amitriptyline (AT) and nortriptyline (NT) in turn, in a crossover design. Steady-state plasma drug levels were compared with those calculated for eight healthy subjects of previous single-dose studies. Plasma clearances were on average about 2.5 time