Sympathetic sprouting and changes in nociceptive sensory innervation in the glabrous skin of the rat hind paw following partial peripheral nerve injury

Peripheral nerve injury leads to the est

Peripheral nerve injury leads to the establishment of a novel pattern of sympathetic fibre innervation in the rat skin

✍ Ruocco, Isabella; Cuello, A. Claudio; Ribeiro-Da-Silva, Alfredo 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 695 KB

Peripheral nerve injury has been shown to result in sympathetic fibre sprouting around dorsal root ganglia (DRG) neurons. It has been suggested that this anomalous sympathetic fibre innervation of the DRG plays a role in neuropathic pain. Other studies have suggested an interaction between sympathet