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Symbolic programs for structural identification of linear pharmacokinetic systems

โœ Scribed by Randall C Manaka; Alan Schumitzky; Walter Wolf

Publisher
Elsevier Science
Year
1981
Weight
614 KB
Volume
13
Category
Article
ISSN
0010-468X

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โœฆ Synopsis

Most parameter estimation techniques implicitly assume that it is possible to determine the parameters of the system uniquely if there were no noise in the output. In practice, this is not always the case. Whether or not this assumption is true for a given input-output experiment is the problem of structural identification.

Two programs utilizing symbolic matrix calculus are presented which aid in solving this problem for linear systems. Pharmacokinetic examples are given.

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