✦ LIBER ✦

Swinholide-A, a new marine macrolide. Complete assignment of 1H and 13C spectra by 2D NMR techniques

✍ Scribed by Shmuel Carmely; Michal Rotem; Yoel Kashman

Publisher: John Wiley and Sons
Year: 1986
Tongue: English
Weight: 738 KB
Volume: 24
Category: Article
ISSN: 0749-1581
DOI: 10.1002/mrc.1260240414

No coin nor oath required. For personal study only.

✦ Synopsis

H and =CNMR spectra of the novel marine macrolide swinholide-A, which provide the basis for its structure elucidation, have been completely assigned by parallel use of 1D and homo-and hetero-nuclear 2D NMR techniques. Swinholide-A (1) probably a polyketide, is a 22-membered macrolide embodying a dihydropyran ring and a 10-carbon side-chain ending with a substituted tetrahydropyran ring. The high degree uf overlap of eleven CH-0 and nine CH, signals in the 1D proton NMR spectrum of 1 necessitated the structure elucidation of swinholide-A tetraformate (2) by 2D homo-(up to 6J with formyl groups) and hetero-nuclear NMR correlations. Formyl groups can be good structural probes in complex polyalcohols, as shown by the observed "J and 6J formate couplings in 2.

📜 SIMILAR VOLUMES

Complete 1H and 13C NMR spectral assignm

Complete 1H and 13C NMR spectral assignment of venturicidin A by 2D NMR spectroscopy

✍ Adolf Gogoll; David Tanner 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 English ⚖ 664 KB

After correlation of the majority of signals by COSY and one-bond heteronuclear correlation, the complete assignment of the 'H and I3C NMR spectra of the macrolide antibiotic venturicidin A required the application of long-range CH coupling information. This was accessible by the COLOC-S and selecti

Complete assignment of 1H and 13C NMR sp

Complete assignment of 1H and 13C NMR spectra of ikarisoside A and epimedoside C

✍ Wen-Kui Li; Pei-Gen Xiao; Jing-Qi Pan 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 130 KB 👁 2 views

The complete assignment of the proton and carbon NMR spectra for ikarisoside A and epimedoside C from the aerial parts of Epimedium koreanum were achieved using the concerted application of one-and two-dimensional NMR techniques including COSY and HMBC spectroscopy. The parameters previously reporte

Complete 1H and 13C assignment of some c

Complete 1H and 13C assignment of some cubane derivatives by 2D NMR spectroscopy

✍ T. Axenrod; B. Liang; A. Bashir-Hashemi; P. R. Dave; D. S. Reddy 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 227 KB

Complete assignment of the 1H and 13C NM

Complete assignment of the 1H and 13C NMR spectra of a new polyester sesquiterpene from Austroplenckia populnea

✍ S. A. Vieira Filho; L. P. Duarte; M. H. Santos; G. D. F. Silva; I. S. Lula; R. J 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 58 KB 👁 2 views

Unequivocal total assignment of 13C and

Unequivocal total assignment of 13C and 1H NMR spectra of some pyrido[1,2-a]pyrimidine derivatives by 2D-NMR

✍ Krishan A. Suri; Om P. Suri; Musarat Amina; Basant P. Wakhloo; Naresh K. Satti 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 80 KB 👁 1 views

## Abstract We report the total assignments of the ^13^C and ^1^H NMR spectra of some 4‐methyl‐2‐oxo‐(2__H__)‐pyrido[1,2‐__a__]pyrimidine and 2‐methyl‐4‐oxo‐(4__H__)‐pyrido[1,2‐__a__]pyrimidine derivatives. The products were characterized by ^1^H and ^13^C NMR and reported data for similar compound

Complete Signal Assignment of the 13C-NM

Complete Signal Assignment of the 13C-NMR Spectra and Structure Determination of Corrinoids by 2D-INADEQUATE and 2D 13C, 1H-NMR Chemical Shift Correlation Using nJ(C,H)

✍ Dr. Reinhard Benn; Dr. Richard Mynott 📂 Article 📅 1985 🏛 John Wiley and Sons 🌐 English ⚖ 345 KB 👁 2 views