✦ LIBER ✦

Swimming capacity of mice after prolonged treatment with psychostimulants

✍ Scribed by C. -J. Estler; Monika C. Gabrys

Book ID: 104771768
Publisher: Springer
Year: 1979
Tongue: English
Weight: 379 KB
Volume: 60
Category: Article
ISSN: 0033-3158
DOI: 10.1007/bf00432289

No coin nor oath required. For personal study only.

✦ Synopsis

Swimming endurance and availability of metabolic substrates (blood glucose and nonesterified fatty acids [NEFA], liver and muscle glycogen, body fat) were studied in mice treated with 10pg/g methamphetamine/day for 6 weeks. At the end of the 6-week treatment, motor coordination of the methamphetamine-treated animals was much better than that of controls, and swimming capacity tended to increase. While swimming, mice treated with methamphetamine mobilized more glycogen from the hepatic stores and utilized glucose more effectively. Their NEFA levels in blood were higher than those of controls. There was no difference in the muscular glycogen content.

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