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Swelling and drug release behaviour of xanthan gum matrix tablets

โœ Scribed by M.M. Talukdar; R. Kinget

Book ID
113366582
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
744 KB
Volume
120
Category
Article
ISSN
0378-5173

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Sustained-release and swelling character
Sustained-release and swelling characteristics of xanthan gum/ethylcellulose-based injection moulded matrix tablets: in vitro and in vivo evaluation
โœ T. Quinten; T. De Beer; F. O. Onofre; G. Mendez-Montealvo; Y. J. Wang; J. P. Rem ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 419 KB

Sustained-release matrix tablets were developed by injection moulding using metoprolol tartrate (MPT) and ethylcellulose (EC) as sustained-release agent. Dibutyl sebacate was selected as plasticiser. The influence of matrix composition, plasticiser concentration, and drug load on drug release was ev