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Sweat chloride and ΔF508 mutation in chronic bronchitis or bronchiectasis

✍ Scribed by Radj Gervais; Jean-Jacques Lafitte; Viviane Dumur; Maryse Kesteloot; Guy Lalau; Nicole Houdret; Philippe Roussel


Book ID
119066692
Publisher
The Lancet
Year
1993
Tongue
English
Weight
171 KB
Volume
342
Category
Article
ISSN
0140-6736

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Genotype analysis for ΔF508, G551D and R
✍ Dr. Ann Duthie; Derek G. Doherty; Carolyn Williams; Robert Scott-Jupp; J. O. War 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 613 KB

Genetic factors have been implicated in the pathogenesis of liver disease in cystic fibrosis. To investigate whether liver disease is associated with particular mutations of the defective gene in cystic fibrosis, we have determined the frequencies of three mutations -AF508, G551D and R553X-in 111 ch