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SV40 Pseudovirion gene delivery of a toxin to treat human adenocarcinomas in mice

✍ Scribed by Kimchi-Sarfaty, C; Vieira, W D; Dodds, D; Sherman, A; Kreitman, R J; Shinar, S; Gottesman, M M

Book ID: 110019343
Publisher: Nature Publishing Group
Year: 2006
Tongue: English
Weight: 238 KB
Volume: 13
Category: Article
ISSN: 0929-1903
DOI: 10.1038/sj.cgt.7700943

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## Abstract ## Background Current liposome‐based gene delivery methods for therapeutic benefit are limited by their low efficiency. One possible way to improve gene expression is to include a peptide with a nuclear localization signal (NLS) to enhance the movement of the transfection complex from