SV40 A gene required to maintain transformation?
- Book ID
- 109695476
- Publisher
- Nature Publishing Group
- Year
- 1975
- Tongue
- English
- Weight
- 243 KB
- Volume
- 255
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/255367a0
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Amplification of SV40 genes in SV40βtransformed Chinese hamster embryo cells (CO631) by chemical carcinogens as well as by herpes simplex virus infection can be inhibited by infection with the defective parvovirus, AAVβ5. This is shown by __in situ__ hybridization with SV40 DNA of AAVβ5
## Abstract Transformation of mouse 3T3 cells by SV40 results in a specific membrane modification which renders cells resistant to the killing action of the lipophilic antibiotic Amphotericin B. This alteration is under genetic cellular control and is specific for SV40 transformation since transfor
## Abstract Gene amplification contributes to carcinogenesis by enhancing protoβoncogene activity and causing chromosomal instability. The ease of detecting amplified tumorβvirus sequences has encouraged use of this system as a surrogate for studying the molecular events involved in endogenous gene