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Sustained remission of metastatic adrenal carcinoma during long-term administration of low-dose mitotane

✍ Scribed by Ilias, I.; Alevizaki, M.; Philippou, G.; Anastasiou, E.; Souvatzoglou, A.

Book ID
125334812
Publisher
Springer-Verlag
Year
2001
Tongue
English
Weight
185 KB
Volume
24
Category
Article
ISSN
0391-4097

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Plasma level monitoring of mitotane (o,p'-DDD) and its metabolite (o,p'-DDE) during long-term treatment of cushing's disease with low doses
✍ R. Benecke; E. Keller; B. Vetter; R. A. Zeeuw πŸ“‚ Article πŸ“… 1991 πŸ› Springer 🌐 English βš– 345 KB

Mitotane (o,p'-DDD) can be used for the treatment of various adrenocortical diseases such as Cushing's syndrome, but the usual doses of 6-8 g per day are often associated with severe adverse effects. This paper reports the results of much lower doses of o,p'-DDD (0.5-2 g per day) in two patients wit