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Sustained Release of a Water-Soluble Drug from Alginate Matrix Tablets Prepared by Wet Granulation Method

โœ Scribed by Sanchita Mandal; Sanat Kumar Basu; Biswanath Sa


Book ID
111768077
Publisher
Springer US
Year
2009
Tongue
English
Weight
309 KB
Volume
10
Category
Article
ISSN
1530-9932

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Sustained-release formulations such as hydroxypropyl methylcellulose (HPMC)based hydrophilic matrix tablets of poorly water-soluble drugs often result in incomplete release because of the poor solubility and dissolution rate of the drug in the hydrophilic matrix. Sulfobutylether-b-cyclodextrins ((SB