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Sustained-Release Delivery of Octreotide from Biodegradable Polymeric Microspheres

✍ Scribed by Yun-Seok Rhee; MinJi Sohn; Byung H. Woo; B. C. Thanoo; Patrick P. DeLuca; Heidi M. Mansour


Book ID
118729061
Publisher
Springer US
Year
2011
Tongue
English
Weight
331 KB
Volume
12
Category
Article
ISSN
1530-9932

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New models are developed to account for the kinetics of drug release from porous, biodegradable polymeric microspheres under the schemes of bulk erosion and surface erosion of the polymer matrix, respectively. Three mechanisms of drug release, namely, drug diffusion, drug dissolution, and polymer er