✦ LIBER ✦

Susceptibility to lupus nephritis in the NZB/W model system

✍ Scribed by Laurence Morel; Edward K Wakeland

Book ID: 104358870
Publisher: Elsevier Science
Year: 1998
Tongue: English
Weight: 625 KB
Volume: 10
Category: Article
ISSN: 0952-7915
DOI: 10.1016/s0952-7915(98)80094-0

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✦ Synopsis

Advances in genetic mapping have resulted in the identification of multiple lupus susceptibility loci in the NZB/W mouse model. The analysis of congenic strains carrying these loci is now providing functional data on their role in lupus pathogenesis and is paving the way to the identification of the susceptibility genes and their molecular characterization.

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