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Survivorship considerations in adults with hereditary breast and ovarian cancer syndrome: state of the science

✍ Scribed by Cheryl B. Crotser; Marcia Boehmke

Publisher
Springer-Verlag
Year
2009
Tongue
English
Weight
291 KB
Volume
3
Category
Article
ISSN
1932-2259

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## BACKGROUND. The hereditary nonpolyposis colorectal carcinoma (HNPCC) syndrome is an autosomal dominant genetic disorder caused by the inheritance of a mutation in one of a family of genes encoding DNA mismatch repair (MMR) proteins. HNPCC manifests as genetic instability in linked tumors. Clini