Survivor ion mass spectrometry

✍ Scribed by Frantisek Turecek; Ming Gu

• Book ID: 102559483
• Publisher: John Wiley and Sons
• Year: 1992
• Tongue: English
• Weight: 167 KB
• Volume: 27
• Category: Article
• ISSN: 1076-5174
• DOI: 10.1002/oms.1210271132

✦ Synopsis

OMS Letter

Dear Sir

Survivor Ion Mass Spectrometry Differentiation of valence-bond isomers and stereoisomers has been a pivotal topic in mass spectrometry, and various tandem mass spectrometric methods have been developed to distinguish isomers through their ionic' or neutral' dissociations. In this paper we present a new method based on the simultaneous neutralization and reionization of all stable ions produced in the ion source followed by selective monitoring of non-dissociating species. This survivor ion mass spectrometry 65 1 C I 1 d achieves isomer differentiation in a single spectrum while providing information on all stable ions, as opposed to the conventional tandem mass spectrometry, where a matrix of spectra must be acquired in order to characterize two or more precursor ions. The survivor ion mass spectrum has a potential of pointing out structure-significant ion species to be selected for further a n a l y ~i s . ~

In the present technique all ions produced in the ion source are transmitted by a q u a d r u p l e mass analyzer, accelerated to 8 keV: and converted to fast neutrals by collisions with Xe.2b After several )IS the neutral species are reionized by collisions 0 9 l o b ' 1 1 0 .