Survival of skin allografts following embryonic limb bud transplants in the turtle, Chelydra serpentina

✍ Scribed by C. L. Yntema

• Book ID: 102370532
• Publisher: John Wiley and Sons
• Year: 1974
• Tongue: English
• Weight: 458 KB
• Volume: 144
• Category: Article
• ISSN: 0362-2525
• DOI: 10.1002/jmor.1051440407

✦ Synopsis

Abstract

Allografts of skin were observed in Chelydra serpentina. The response to these grafts was modified by a previous transplantation of a limb bud at an early embryonic stage. When the same donor was used for all transplants, the first skin graft was accepted by the host. A second skin graft, however, was rejected at about the rate of a simple first set allograft of skin. The animals were conditioned by the embryonic limb graft; this embryonic graft can be undergoing rejection at the same time a first set skin graft from the same donor was being accepted. The tolerance induced by the embryonic graft was sepcific for its donor.