C-erbB receptor/neuregulin signalling plays a significant role in Schwann cell function. In vivo, Schwann cells up-regulate expression of c-erbB receptors in the first month after injury, but receptor expression is down-regulated with time to levels that are not detectable immunohistochemically. The
Survival of Schwann cells in chronically denervated skeletal muscles
β Scribed by Eduard I. Dedkov; Tatiana Y. Kostrominova; Andrei B. Borisov; Bruce M. Carlson
- Book ID
- 106072772
- Publisher
- Springer-Verlag
- Year
- 2002
- Tongue
- English
- Weight
- 411 KB
- Volume
- 103
- Category
- Article
- ISSN
- 0001-6322
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There are several differences between red and white muscles submitted to different experimental conditions, especially following denervation: a) denervation atrophy is more pronounced in red than white muscles; b) the size of the fibers in the red muscles does not vary between different parts of the
We have tested the stimulation of Schwann cell migration from the distal stump of a 1 week transected sciatic nerve of adult rats by denervated skeletal muscle. Migrating Schwann cells were distinguished by the presence of non-specific cholinesterase (nChE) activity and glial fibrillary acidic prote