Survival of docetaxel-resistant prostate cancer cells in vitro depends on phenotype alterations and continuity of drug exposure
β Scribed by A. N. Makarovskiy; E. Siryaporn; D. C. Hixson; W. Akerley
- Book ID
- 105757524
- Publisher
- Springer
- Year
- 2002
- Tongue
- English
- Weight
- 214 KB
- Volume
- 59
- Category
- Article
- ISSN
- 1420-682X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Because solid growing tumors often show hypoxia and pronounced extracellular acidosis, the aim of this study was to analyze the impact of an acidotic environment on the activity of the pβglycoprotein (pGP) and on the cellular content and cytotoxicity of the chemotherapeutic drug daunoru
## Abstract Prolonged hypoxia induced transient drug resistance in Chinese hamster lung fibroblasts. Previously hypoxic cells were resistant to adriamycin and resistant to etoposide. Complete recovery of etoposide sensitivity was observed following reβaeration for 24 hr. A change in Pβglycoprotein