A cohort of 917 Down syndrome (DS) children born in Italy between 1978 and 1984 was studied for survival through the age of 8 years. The highest mortality occurred in the first month of life (7.%); survival was about 80% at 1 year, 78% at 2 years, and 76% at 5 years, with small decreases thereafter.
Survival of children with cancer in torino, Italy
β Scribed by Magnani, C. ;Pastore, G. ;Cesana, B. ;Di Prima, S. ;Stalteri, D. ;Terracini, B.
- Publisher
- John Wiley and Sons
- Year
- 1983
- Tongue
- English
- Weight
- 404 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0098-1532
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β¦ Synopsis
During 1967-78, cancer was diagnosed in 870 children living in the Province of Torino. Survival until the end of 1978 is reported separately for cases diagnosed in 1967-70, in 1971-74, and in 1975-78. Comparisons between the three series indicate a statistically significant (p less than 0.05) increase in survival rates for children with leukemia and cancer of the central nervous system as well as a nonstatistically significant increase for children with lymphoma (both Hodgkin's and non-Hodgkin's). No consistent changes in time were noticed for neuroblastomas, nephroblastomas, soft tissue sarcomas, and retinoblastomas. Survival rates for both types of lymphomas and for leukemias (at least for cases diagnosed after 1975) were very similar to corresponding population-derived data from the U.S. and other Western countries. Rates for other cancers were relatively poor in the Province of Torino. It is suggested that relatively high care standards are easier to achieve in the case of childhood cancers requiring chemotherapy than in cancers commonly treated through radiotherapy and/or surgery.
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