Survival of breast-cancer patients and body size indicators

✍ Scribed by Shinji Kyogoku; Tomio Hirohata; Setsuko Takeshita; Yasuo Nomura; Takao Shigematsu; Akio Horie

• Publisher: John Wiley and Sons
• Year: 1990
• Tongue: French
• Weight: 717 KB
• Volume: 46
• Category: Article
• ISSN: 0020-7136
• DOI: 10.1002/ijc.2910460513

✦ Synopsis

The association of breast-cancer survival with various risk factors was investigated using data of 2 I 3 breast-cancer patients who underwent surgical operation between I975 and 1978. They were followed-up until 1987, and a total of 64 deaths including 47 breast-cancer deaths were certified. The 5-year and 10-year relative survival rates were 78.5% and 75.3% respectively. Of the various factors investigated, some anthropometric indicators revealed interesting results; i.e., body weight, Quetelet index, and body surface area at the time of operation turned out to be strong predictors of survival with a statistically significant trend towards lower survival with larger body structure even after adjustment for confounding factors (e.g., clinical stage) using a proportionalhazard model. The estimated survival probability for women with Quetelet index of 20 was about 12% higher than that with Quetelet index of 24 over a 10-year or more follow-up period. Other variables exhibiting prognostic importance were clinical stage, TNM classification, and some histological findings, while height and reproductive life indicators were, as a rule, not significantly related to survival. 5To whom correspondence and reprint requests should be sent.