Model-based prediction of defective DNA
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Frank Sinicrope; Nathan R. Foster; Daniel J. Sargent; Stephen N. Thibodeau; Thom
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Article
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2010
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John Wiley and Sons
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English
⚖ 149 KB
## Abstract ## BACKGROUND: Colon cancers with defective DNA mismatch repair (MMR) have a favorable prognosis and may lack benefit from 5‐fluorouracil–based adjuvant chemotherapy. The authors developed models to predict MMR deficiency in sporadic colon cancer patients using routine clinical and pat