We read with great interest the article by Cavazza et al., 1 who demonstrated that an advanced histological stage was the only risk factor associated with the development of hepatocellular carcinoma (HCC) in patients with primary biliary cirrhosis (PBC) from two European centers. Similar results wer
Surveillance for hepatocellular carcinoma in patients with primary biliary cirrhosis
โ Scribed by Marina G. Silveira; Ayako Suzuki; Keith D. Lindor
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 139 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0270-9139
No coin nor oath required. For personal study only.
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Surveillance for hepatocellular carcinoma (HCC) in patients with cirrhosis is recommended but may not be performed. The extent and determinants of HCC surveillance are unknown. We conducted a population-based United States cohort study of patients over 65 years of age to examine use and determinants
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An impaired sulfoxidation pathway has been implicated in the pathogenesis of chlorpromazineinduced hepatotoxicity. Since some patients with chronic chlorpromazine-induced cholestasis may have features of primary biliary cirrhosis, we studied the ability to sulfoxidate the amino acid analogue 5'-carb