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Surrogate endpoints for overall survival in locally advanced head and neck cancer: meta-analyses of individual patient data

✍ Scribed by Stefan Michiels; Aurélie Le Maître; Marc Buyse; Tomasz Burzykowski; Emilie Maillard; Jan Bogaerts; Jan B Vermorken; Wilfried Budach; Thomas F Pajak; Kian K Ang; Jean Bourhis; Jean-Pierre Pignon

Book ID: 117784936
Publisher: The Lancet
Year: 2009
Tongue: English
Weight: 349 KB
Volume: 10
Category: Article
ISSN: 1470-2045
DOI: 10.1016/s1470-2045(09)70023-3

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## Abstract ## Background. Although meta‐analysis showed that survival improved with concurrent chemoradiation in locally advanced head and neck cancer, neoadjuvant chemotherapy is still unique, because it renders curative surgery feasible for marginally resectable head and neck cancer patients.