Background. Squamous cell carcinoma (SCCA) of the oral cavity recurs with a frequency of 25%-48%, a fact that usually portends a poor prognosis. Recent studies have reported salvage cure rates as high as 67%. Investigators have also claimed that restaging recurrent tumors provides useful prognostic
Surgical treatment of oral cavity carcinoma
β Scribed by Silver, Carl E. ;Glackin, Brigid K. ;Brauer, Richard J. ;Lesser, Martin L.
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 1986
- Weight
- 470 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0148-6403
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β¦ Synopsis
Ninety-four squamous cell carcinomas of the oral cavity, treated on the author's service between 1969 and 1981, were evaluated. The series included squamous cell carcinomas of various intraoral sites excluding the lips and hard palate. Survical of 60 mo was 70% for stage I, 65% for stage 11, 45% for stage 111, and 27% for stage IV carcinoma. Twenty-four of 34 patients with "early" cancer (stages I and II) were treated by operation alone. Too few patients with "early" cancer were treated by combined irradiation and surgery to draw conclusions regarding relative efficacy of combination therapy. Sixty patients had "advanced" cancer (stages 111 and IV). Five-year survival was 37% for patients treated by operation alone, 18% after salvage surgery after failed irradiation, and 60% for patients treated by operation combined with planned perioperative irradiation. Combination therapy appeared to improve control of locoregional disease as well as survival in patients with "advanced" cancer. HEAD & NECK SURGERY 9:13-18,1986 I n 1978 our service reported the treatment results of 45 cases with oral cavity carcinoma between 1966 and 1976.l During that interval, patients treated surgically in our service fell into two groups, those treated initially by operation alone, and those treated by salvage surgery after failure of initial high-dose radiotherapy. Three-year cure rates for the entire group of patients were 63% for both From the Head and Neck Service, Surgical Division (Drs. Silver, Glackin. and Brauer) and the
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## Abstract Over 90% of malignant tumors of the head and neck are squamous cell cancers. These originate in the epithelium of the upper respiratory and alimentary tracts. Some thirty or more primary sites are recognized. Though there are specific therapeutic problems relative to each of these sites