Surgical treatment of carcinoma of the breast. I. Pathological finding and pattern of relapse

✍ Scribed by Yeu-Tsu N. (Margaret) Lee; Roger Terry

• Publisher: John Wiley and Sons
• Year: 1983
• Tongue: English
• Weight: 427 KB
• Volume: 23
• Category: Article
• ISSN: 0022-4790
• DOI: 10.1002/jso.2930230105

✦ Synopsis

Abstract

This is a retrospective review of 476 patients who had mastectomy for carcinoma of the breast during 1971–1980. There is a positive correlation of size of the primary tumor and the incidence of axillary nodal metastasis. Infiltrating ductal and lobular carcinoma had a significantly higher incidence of nodal metastasis (and greater chance of having four or more positive nodes) than that of medullary and colloid carcinomas. Colloid carcinoma smaller than 4 cm and the less common histological subtypes (comedo, tubular, papillary carcinomas) rarely metastasizes. At a median follow‐up time of 53 months, 23% of patients with infiltrating ductal, lobular, or medullary carcinomas and who did not have nodal metastasis had relapse, while 50% of those with nodal involvement had relapse. Among those who relapsed, 18% initially had only locoregional recurrence, 60% had distant metastasis, and 22% had both types.