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Surfactant Protein A Regulates Pulmonary Surfactant Secretion via Activation of Phosphatidylinositol 3-Kinase in Type II Alveolar Cells

✍ Scribed by Martyn K. White; David S. Strayer


Book ID
115603566
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
503 KB
Volume
255
Category
Article
ISSN
0014-4827

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The fetal lung secretes significant quantities of surfactant during late gestation to prepare for initiation of respiration at birth. However, the mechanism by which this occurs has not been determined. Since Ca 2+ -phosphatidylserine (PS)-dependent protein kinase C has been implicated in surfactant