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Surfactant-Induced Helix Formation of Cylindrical Brush Polymers with Poly(L-lysine) Side Chains

✍ Scribed by Nikhil Gunari; Yang Cong; Bin Zhang; Karl Fischer; Andreas Janshoff; Manfred Schmidt


Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
265 KB
Volume
29
Category
Article
ISSN
1022-1336

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✦ Synopsis


Abstract

The complex formation of oppositely charged surfactants with some polypeptides is known to induce β‐sheet or helix formation. Here, we report on the complex formation of cylindrical brush polymers with poly(L‐lysine) side chains and sodium dodecylsulfate (SDS). With increasing amount of added surfactant the cylindrical polymers first adopt a helical conformation with a pitch of approximately 14–24 nm followed by a spherically collapsed structure before eventually precipitation occurs. CD measurements suggest that the helix formation of the cylindrical brush polymers is driven by the hydrophobicity of the β‐sheets formed by the PLL side chain–SDS complexes.

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