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Surfactant effects on the in vitro percutaneous absorption of diclofenac sodium

✍ Scribed by A. Arellano; S. Santoyo; C. Martn; P. Ygartua

Publisher
Springer-Verlag
Year
1998
Tongue
English
Weight
746 KB
Volume
23
Category
Article
ISSN
0378-7966

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Effect of surfactants on percutaneous ab
Effect of surfactants on percutaneous absorption of naproxen II: In vivo and In vitro correlations in rats
✍ Z. T. Chowhan; R. Pritchard; W. H. Rooks II; A. Tomolonis πŸ“‚ Article πŸ“… 1978 πŸ› John Wiley and Sons 🌐 English βš– 350 KB πŸ‘ 1 views

The effect of surfactants on percutaneous absorption of naproxen was studied using rat in vivo models. The in vivo normalized relative absorption rates were in good agreement with the in vitro relative flux. An antipyretic model in the rat could not show relatively small increases in percutaneous ab